| Dietary contribution to body burden of bisphenol A and bisphenol S among mother-children pairs | |
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| 년도 | 2020 |
| 날짜 | 2020 Nov |
| 페이지 / 학회지명 |
744, 140856 / Science of the Total Environment |
| 논문저자 | Sunmi Kim 1, Inae Lee 1, Jae-Eun Lim 2, Aram Lee 3, Hyo-Bang Moon 2, Jeongim Park 3, Kyungho Choi 4 |
| Link |
https://www.sciencedirect.com/science/article/abs/pii/S004896972034380…
181회 연결
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1 School of Public Health, Seoul National University, Seoul 08826, Republic of Korea; Institute of Health and Environment, Seoul National University, Seoul 08826, Republic of Korea. 2 Department of Marine Science and Convergence Engineering, Hanyang University, Ansan 15588, Republic of Korea. 3 College of Natural Sciences, Soonchunhyang University, Asan 31538, Republic of Korea. 4 School of Public Health, Seoul National University, Seoul 08826, Republic of Korea; Institute of Health and Environment, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: kyungho@snu.ac.kr. Abstract Due to the health concerns over bisphenol A (BPA), bisphenol S (BPS) has been used as an alternative in greater quantity. Diet is considered as the major source of exposure to bisphenols; however, its contribution to the total body burden has not been fully understood. In the present study, a 3-day dietary intervention was carried out for a group of mother and child(ren) pairs (37 families, 93 subjects), and contribution of the dietary factors to body burden of both bisphenols was investigated. During the intervention, the participants were asked to refrain from the foods in cans and plastic containers, fast foods, and delivery foods. Urinary levels of BPA and BPS were measured before, during, and after the intervention. In addition, the questionnaire survey was conducted for potential contributors to BPA and BPS exposure. Following the intervention, urinary levels of BPA and BPS of the mothers decreased on average by 53.1% (95% CI: -30.0, -68.6), and 63.9% (95% CI: -37.1, -79.3), respectively. Among the children, urinary BPA concentrations decreased by 47.5% (95% CI: -25.6, -62.9) by the intervention. However, BPS levels in urine did not change in the children. Interestingly, urinary BPS concentrations of the children measured during the non-intervention period were greater than those of the mothers in the same period. Consumption frequencies of several food items, e.g., canned foods, take-out drinks, or fast foods, were significantly correlated with elevated levels of urinary BPA or BPS concentrations. The results of this intervention study emphasize the importance of dietary contribution to BPA exposure among the mothers and children. Our findings also show that non-dietary sources could be a more important contributor for certain people, especially to BPS exposure among children. Further studies are warranted to identify the sources of BPS exposure among children. Keywords: Bisphenol A (BPA); Bisphenol S (BPS); Dietary exposure; Intervention; Relative exposure contribution. |
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