| Uncertainty-based concentration estimation of chlortetracycline antibiotics in swine farms and risk probability assessment for agricultural application of manure | |
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| 년도 | 2021 |
| 날짜 | 2021 Jan 15 |
| 페이지 / 학회지명 |
402:123763 / Journal of Hazardous Materials |
| 논문저자 | Changmin Lee 1, Jinsung An 2, Young Su Lee 1, Kyungho Choi 3, Jae Young Kim 4 |
| Link |
https://www.sciencedirect.com/science/article/pii/S0304389420317520?vi…
256회 연결
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1 Department of Civil & Environmental Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea. 2 Department of Biological & Environmental Engineering, Semyung University, 65 Semyung-ro, Jecheon-si, Chungcheongbuk-do 27136, Republic of Korea. 3 Department of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea. 4 Department of Civil & Environmental Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea. Electronic address: jaeykim@snu.ac.kr. Abstract Consideration of livestock farming practices is necessary for the reliable prediction of veterinary antibiotics concentrations in livestock manure and soil and characterization of their ecological risks. This study aims to predict concentrations of chlortetracycline (CTC) generated from slurry pit and evaluate its ecological risk in soil based on the European Medicine Agency guidelines by considering slurry pit farm practices such as cleaning water volume and those uncertainties. Additionally, sensitivity analysis was conducted on the exposure estimation of CTC in soil employing the Monte Carlo simulation. The predicted environmental concentrations of CTC in the slurry pit and soil were in a range of 0.54-5.64 mg/kgmanure and 3.42-67.59 μg/kgsoil, respectively, for a 90 % confidence level. The predicted ranges included the measured values reported in previous studies. The probability of risk quotient (RQ) exceeding one was estimated at 9.3 % based on the Monte Carlo simulation. The four most influential factors on the exposure to CTC in soil were identified as nitrogen in fertilizer/compost, cleaning water volume, ratio of sick pigs requiring antibiotics, and pit emptying cycles. The results indicate that the ecological risk of CTC in the soil is possible and can be controlled by slurry pit farm practices. Keywords: Ecological hazard; Livestock manure; Monte Carlo simulation; Risk assessment; Veterinary antibiotics. |
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